Trivieri Lab Research Portfolio

The Trivieri Lab focuses on investigating key molecular mechanisms responsible for the onset and progression of Heart Failure and Pulmonary Hypertension (PH) using state of the art techniques of stem cell biology and tissue engineering. Current research programs are centered on elucidating the role of Phospholamban (PLN) in the pathophysiology of inherited cardiomyopathy as well cutting-edge technologies to model PH using adult stem cells derived smooth muscle and endothelial cells. 

In addition, the Trivieri lab is actively involved in human translation research that utilizes sophisticated molecular imaging tools such as Positron Emission Tomography (PET) coupled with magnetic resonance (MR) to evaluate in vivo a variety of cardiomyopathies (sarcoidosis, amyloidosis, mitral valve diseases, Long-Covid related cardiopulmonary complications and heart transplant rejection) as well as the inflammatory processes underlying Pulmonary Hypertension.